Damon Runyon Researchers

Meet Our Scientists
Emma Watson, PhD

Dr. Watson [Suzanne and Bob Wright Fellow] is taking advantage of high-throughput genetic screens to map gene networks involved in the response to metabolic stress. Cancer cells tap into growth-promoting metabolic programs, enabling them to robustly proliferate using limited resources from the tissue microenvironment and bloodstream. The metabolic plasticity observed in cancer cells can be at least partly attributed to metabolic stress response pathways that enable the cancer to mobilize resources for growth. Identifying the genes involved in sensing and enacting responses to metabolic stress will provide potentially novel therapeutic targets in the treatment of cancer.

Project title: "Metabolic stress response: Exploring transcript-level regulation of metabolic feedback"
Institution: Brigham and Women's Hospital
Named Award: Suzanne and Bob Wright Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): Stephen Elledge, PhD
Cancer Type: All Cancers
Research Area: Genomics