Damon Runyon Researchers

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Daniel J. Blair, PhD

Dr. Blair [Illini 4000 Fellow] aims to address a key bottleneck in drug discovery by developing a generalizable strategy for synthesis of complex natural products to be used as therapeutics. Small molecules created by nature (natural products) often possess extraordinary functional potential and have led to many transformative human medicines. Unfortunately, despite important progress in the field of natural product synthesis, the methods available for synthesizing such complex natural products are typically too slow for practical drug discovery and development. He proposes to break down complex natural products into simple building blocks, which can then be iteratively assembled through automation to generate natural products.

Project title: "An automated small molecule synthesizer for the discovery of new anti-cancer agents"
Institution: University of Illinois, Urbana-Champaign
Named Award: Illini 4000 Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): Martin D. Burke, MD, PhD
Cancer Type: All Cancers
Research Area: Drug Discovery