Damon Runyon Researchers

Meet Our Scientists
Amit J. Sabnis, MD

Dr. Sabnis is exploring novel treatment options for rhabdomyosarcomas, the most common pediatric soft tissue sarcomas. These sarcomas uniquely depend on the activity of "protein chaperones" that prevent newly made proteins from forming toxic clumps. His research focuses on small molecules that inhibit one class of chaperones called HSP70s. The goal of these studies is to identify a new target for drug development to help cure this disease.


Project title: "Exploiting chaperone dependence as a novel therapeutic strategy in alveolar rhabdomyosarcoma"
Institution: University of California, San Francisco
Award Program: Sohn Fellow
Sponsor(s) / Mentor(s): Trever G. Bivona, MD, PhD
Cancer Type: Pediatric, Sarcoma
Research Area: Experimental Therapeutics