Damon Runyon Researchers

Meet Our Scientists
Shuibin Lin, PhD

Dr. Lin studies neuroblastoma cancers. Genetic amplification and aberrant expression of the oncogenes LIN28B and MYCN are associated with high-risk neuroblastoma and poor survival. Interestingly, these genes positively regulate each other and form a self-reinforcing feedback loop to drive neuroblastoma oncogenesis. His research aims to identify novel factors that interact with LIN28B/MYCN in tumor formation. He is characterizing a LIN28B-interacting long intergenic non-coding RNA (lincRNA) and will determine how the lincRNA functions to regulate neuroblastoma progression.


Project title: "Molecular and cellular characterization of a novel LincRNA in neuroblastoma"
Institution: Boston Children's Hospital
Award Program: Sohn Fellow
Sponsor(s) / Mentor(s): Richard Gregory, PhD
Cancer Type: Other Cancer, Pediatric
Research Area: Carcinogenesis