Damon Runyon Researchers

Meet Our Scientists
Lucy Liu, PhD

Dr. Liu studies cachexia, a complex metabolic syndrome characterized by a rapid and irreversible loss of body mass, which significantly impedes disease treatment success. This body-wasting phenomenon is a common feature in many types of cancers, but the causes are unknown. She is investigating the tumor-derived signaling mechanisms that lead to systemic cachexia and muscle wasting. As no current therapies exist for the reversal or delay of cachexic symptoms, identifying the triggers that lead to systemic body mass loss is imperative to improve our understanding of all cancers and to identify putative drug targets.

Project title: "In vivo characterization of muscle autophagy in health and disease"
Institution: Harvard Medical School
Award Program: Fellow
Sponsor(s) / Mentor(s): Norbert Perrimon, PhD
Cancer Type: All Cancers
Research Area: Cancer Genetics