Damon Runyon Researchers

Meet Our Scientists
Aaron D. Viny, MD

Dr. Viny [William Raveis Charitable Fund Fellow] is studying the oncogenic role of abnormalities in the cohesin complex-a group of proteins that function to align and stabilize sister chromatids (copies of the chromosomes) during cell division.  Mutations within several proteins in this complex have been identified in solid tumors and hematologic malignancies, particularly acute myeloid leukemia, the most common adult leukemia. Although it was presumed these mutations would result in unbalanced chromosomal breaks, this outcome has not yet been observed. He is exploring the mechanistic role of cohesin mutations in cancer pathophysiology and is investigating novel targeted therapies to block this pathway.

Project title: "Role of the cohesin complex in oncogenic transformation of AML"
Institution: Memorial Sloan Kettering Cancer Center
Named Award: William Raveis Charitable Fund Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): Ross L. Levine, MD
Cancer Type: Blood
Research Area: Cancer Genetics