Damon Runyon Researchers

Meet Our Scientists
Srinjoy Chakraborti, PhD

Dr. Chakraborti is developing technologies to facilitate the rapid identification of individual, specific, safely targetable tumor antigens, and to engineer tumor chimeric antigen receptors (CARs) to specifically recognize and kill cancer cells within a clinically relevant timeline. Dr. Chakraborti also plans to use these technologies to investigate the role of helper T cells in enhancing the activity of anti-cancer killer T cells. These technologies, although applicable to adult cancers as well, will focus on antigens derived from pediatric cancer tissues because conventional therapies (such as chemotherapy and radiation) hold long-term health risks. 

Project title: "Mining pHLA and T cell receptors (TCR) specificities by phage display for de novo TCR engineering and personalized cancer therapy"
Institution: Albert Einstein College of Medicine
Award Program: Sohn Fellow
Sponsor(s) / Mentor(s): Jonathan R. Lai, PhD
Cancer Type: Pediatric, All Cancers
Research Area: Immunotherapy