Damon Runyon Researchers

Meet Our Scientists
Tyler Starr, PhD

Dr. Starr focuses on the process of how the immune system produces antibodies that specifically recognize and bind to antigens on pathogens and cancer cells. Dr. Starr is combining computational analyses of antibody sequences with experimental methods to test the effects of possible mutations on antibody function. This iterative process, similar to what the body does naturally, will help identify the best antibodies for an infection. The results of this research may lead to HIV therapeutics that reduce the incidence of AIDS-related cancers and improve the development of antibody-based cancer immunotherapies.

Project title: "The sequence-function landscape of antibody affinity maturation"
Institution: Fred Hutchinson Cancer Research Center
Award Program: Fellow
Sponsor(s) / Mentor(s): Jesse D. Bloom, PhD, and Frederick Matsen, PhD
Cancer Type: All Cancers
Research Area: Evolution