Damon Runyon Researchers

Meet Our Scientists
Lexy von Diezmann, PhD

Dr. von Diezmann studies how cells control the pathways used to repair DNA. Errors in DNA repair contribute to the development of many cancers, such as breast, ovarian, and pancreatic cancers. Dr. von Diezmann will explore the basic principles governing the DNA damage response by examining how a specific subtype of homologous repair enzymes functions in reproductive cells of the model organism C. elegans. Her project will provide mechanistic insight into how changes in the liquid-like organization of proteins at sites of DNA damage regulate repair, supporting the development of novel chemotherapies that modulate the DNA damage response.

Project title: "State changes of a liquid-like compartment monitor crossover recombination"
Institution: University of Utah
Named Award: The Mark Foundation for Cancer Research Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): Ofer Rog, PhD, and Erik Jorgensen, PhD
Cancer Type: All Cancers
Research Area: Chromosome and Telomere Biology