Damon Runyon Researchers

Meet Our Scientists
Erin E. Duffy, PhD

Dr. Duffy is investigating how neuronal activity can regulate gene expression through a potentially novel mechanism in the developing brain, called RNA turnover. This mechanism may enable gene expression to be rapidly and locally controlled at individual connections between neurons based on neuronal activity. There is evidence that neuronal activity may contribute to pediatric malignant glioma brain tumors. Dr. Duffy aims to characterize this process and identify new therapeutic targets for pediatric brain cancer.

Project title: "Activity-dependent changes in RNA stability as a mechanism for synaptic plasticity"
Institution: Harvard Medical School
Award Program: Fellow
Sponsor(s) / Mentor(s): Michael E. Greenberg, PhD
Cancer Type: Brain
Research Area: Neuroscience