Damon Runyon Researchers

Meet Our Scientists
Julia Su Zhou Li, PhD

Dr. Li focuses on how cells become cancerous when they have an abnormal number of chromosomes or broken parts of a chromosome. The centromere, which joins two arms of a chromosome, is essential for faithful chromosome segregation during cell division and genome stability. When chromosomes fail to be delivered correctly to each new cell, the abnormal chromosomes may form “neocentromeres” which have been discovered in developmental disorders and cancer. Dr. Li is developing tools to examine and manipulate these neocentromeres, which may lead to a better understanding of how cancer cells evolve and potentially novel anti-tumor strategies.

Project title: "Spatial regulation of the inheritance of genomic abnormalities in cancer cells"
Institution: Ludwig Institute for Cancer Research
Award Program: Fellow
Sponsor(s) / Mentor(s): Don Cleveland, PhD
Cancer Type: Blood, Sarcoma
Research Area: Chromatin Biology