Damon Runyon Researchers

Meet Our Scientists
Gregory S. Ducker, PhD

One of the unique features of liver cancer is the way in which it obtains and uses different forms of energy, especially fats. Drs. Evason and Ducker found that a certain type of fat (phosphatidylcholine lipids) is elevated in both zebrafish and human liver cancer cells. They are using zebrafish, which form tumors similar to the human disease and can be easily manipulated to study liver cancer. The goal of this project is to determine why phosphatidylcholine lipid levels are higher in liver cancer and how they might be targeted with drugs to prevent or cure this disease.

Project title: "Targeting phosphatidylcholine metabolism in liver cancer using zebrafish"
Institution: Huntsman Cancer Institute at the University of Utah
Award Program: Innovator
Cancer Type: Other Cancer
Research Area: Animal Models/Mouse Models