Damon Runyon Researchers

Dr. Han [Fayez Sarofim Fellow] is developing novel methodologies to fine-tune cellular signaling pathways that may prevent tumor formation and promote regeneration through the Hedgehog pathway. This pathway plays a central role in regulating embryonic tissue patterning and postnatal tissue renewal. Dr. Han will take an interdisciplinary approach combining chemical biology, protein engineering, and computational modeling to examine the Hedgehog pathway in a cell-type specific and spatiotemporally resolved manner. This work aims to provide mechanistic insights into the function of Hedgehog signaling in tissue repair and establish new therapeutic approaches for regenerative medicine.