Damon Runyon Researchers

Meet Our Scientists
Seungsoo Kim, PhD

Dr. Kim [HHMI Fellow] is studying the molecular links between cancer cells undergoing metastasis and formation of the face during development (known as craniofacial development). Both craniofacial and cancer cells must enter a migratory state triggered by certain key transcription factors including TWIST1. However, the exact role of TWIST1 appears to vary across cell types, which might explain some of the differences between cells found in various cancers and in normal craniofacial development. Dr. Kim is using genomic tools to dissect how transcription factor cooperation may toggle TWIST1 function across cell types, with potential implications for all cancers.

Project title: "Transcription factor cooperation shaping TWIST1 multifunctionality across craniofacial development and cancer metastasis"
Institution: Stanford University
Named Award: HHMI Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): Joanna K. Wysocka, PhD
Cancer Type: All Cancers
Research Area: Chromatin Biology