Damon Runyon Researchers

Meet Our Scientists
Edie I. Crosse, PhD

Myelodysplasia and acute myeloid leukemia are blood cancers with a poor prognosis. At the root of these malignancies are cells harboring mutant forms of proteins with dysfunctional activity which results in abnormal cell behavior and drives disease progression. The focus of my project is the development of new therapeutics that precisely identify cells with mutant forms of the proteins and, by harnessing their aberrant biological activity, causes those cells to self-destruct. These selective therapeutics will be able to kill cancer cells but leave the healthy cells intact proving more effective and having less side-effects than the chemotherapies currently in use.

Project title: "Precision therapeutics for hematologic malignancies with splicing factor mutations"
Institution: Fred Hutchinson Cancer Research Center
Named Award: Illini 4000 Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): Robert Bradley, PhD
Cancer Type: Blood, All Cancers
Research Area: Cancer Genetics