Damon Runyon Researchers

Meet Our Scientists
Liron Bar-Peled, PhD

Dr. Bar-Peled is exploring how the protease Caspase-8 regulates T cell activation, which represents a critical step in the adaptive immune response to cancer. While Caspase-8 has long been appreciated to be essential for T cell activation, the molecular mechanisms underlying its role in this process remain poorly understood. His work will focus on identifying and characterizing the proteins cleaved by Caspase-8, which may provide additional therapeutic avenues to activate T cells to target malignant cells in cancer patients.


Project title: "Identification of cysteine liabilities in NRF2-driven cancers"
Institution: The Scripps Research Institute
Named Award: Lallage Feazel Wall Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): Benjamin F. Cravatt, PhD
Cancer Type: Lung, All Cancers
Research Area: Chemical Biology