Damon Runyon Researchers

Meet Our Scientists
Ryan Y. Muller, PhD

Epstein-Barr Virus (EBV) is known to cause several human cancers, including nasopharyngeal cancer, gastric cancer, and B-cell lymphomas. During the early stages of viral infection, EBV induces a state of rapid cell division in host cells that promotes oncogenesis. Dr. Muller [HHMI Fellow] studies specific regions of RNA, known as stable introns, which are expressed at abundant levels during early infection but whose role in the viral lifecycle and during oncogenesis is unknown. Investigating how stable introns influence the host cell's biology may reveal insights into EBV-driven oncogenesis and provide a general understanding of the mechanisms that drive cancer progression. Dr. Muller received his PhD from the University of California, Berkeley and his BS from Arizona State University, Tempe.


Project title: "Excised stable introns of Epstein-Barr virus: functions and mechanisms"
Institution: Whitehead Institute for Biomedical Research
Named Award: HHMI Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): David P. Bartel, PhD
Cancer Type: Gastric
Research Area: RNA (RNA processing, miRNA and piRNA mechanisms, enzymatic RNAs, etc.)