Damon Runyon Researchers

Meet Our Scientists
Antoine Molaro, PhD

Dr. Molaro studies how an ancient "evolutionary arms race" between Krab-Zinc-Finger genes (KZNFs) and DNA sequence elements called retrotransposons has shaped transcriptional networks of stem cells and pluripotency. Because many cancers dedifferentiate to a stem cell-like state, refined knowledge about how KZNFs act to finely modulate transcriptional control may prove essential for the development of new cancer drugs. 

Project title: "Evolutionary and functional consequences of genetic conflicts between KRAB-Zinc-Fingers and endogenous retroviruses in primate genomes"
Institution: Fred Hutchinson Cancer Research Center
Award Program: Fellow
Sponsor(s) / Mentor(s): Harmit S. Malik, PhD
Cancer Type: All Cancers
Research Area: Evolution