Damon Runyon Researchers

Meet Our Scientists
Antonio Cuevas-Navarro, PhD

Dr. Cuevas-Navarro’s [Berger Foundation Fellow] research project focuses on targeting mutations in the RAS genes (HRAS, NRAS, and KRAS), present in about 30% of cancer patients and notorious for driving aggressive tumor growth. Dr. Cuevas-Navarro aims to mitigate these mutations’ effects by using pharmacological agents to enhance a biochemical process that regulates RAS proteins. His project will investigate the mechanism of action of these compounds and assess their effectiveness in patient-derived cancer models. This research has the potential to expand treatment options across various cancer types, including those where current treatments are limited. Dr. Cuevas-Navarro received his PhD from University of California, San Francisco and his BS from University of California, Davis.

Project title: "Elucidating mechanisms that reverse the detrimental effect of RAS mutations in cancer"
Institution: Memorial Sloan Kettering Cancer Center
Named Award: Berger Foundation Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): Piro Lito, MD, PhD
Cancer Type: All Cancers
Research Area: Biochemistry