Damon Runyon Researchers

Meet Our Scientists
William Razzell, PhD

Dr. Razzell [HHMI Fellow] is using cell biological, molecular genetic, and biophysical approaches to understand how cell-derived mechanical forces contribute to tumorigenesis through the modulation of cellular signaling pathways. One pathway that is responsive to mechanical forces is the Hippo pathway, which prevents excessive tissue growth during development. Characterizing how cell-derived forces control normal Hippo signaling will provide insight into the mechanisms by which Hippo pathway misregulation contributes to tumor progression.

Project title: "The role of tension in Hippo pathway signaling"
Institution: Memorial Sloan Kettering Cancer Center
Named Award: HHMI Fellow
Award Program: Fellow
Sponsor(s) / Mentor(s): Jennifer A. Zallen, PhD
Cancer Type: Blood, All Cancers
Research Area: Developmental Biology