New Discoveries and Honors in Cancer Research

Read the latest cancer research and recognition from the members of the Damon Runyon scientific circle.
April 20, 2015
Combination therapy for treatment of advanced melanoma

Jedd D. Wolchok, MD, PhD (Damon Runyon-Lilly Clinical Investigator ‘03-‘08) and colleagues at Memorial Sloan Kettering Cancer Center, New York, reported the results of a Phase I study testing a combination therapy (Yervoy plus Opdivo/nivolumab) vs. Yervoy alone in patients with metastatic melanoma (with wild type BRAF gene). In 72 patients, the rate of confirmed response was 61% for the combination therapy (22% with complete response) vs. 11% for Yervoy alone (0% complete response). These results were published in the journal The New England Journal of Medicine.