New Discoveries and Honors in Cancer Research

Read the latest cancer research and recognition from the members of the Damon Runyon scientific circle.
April 1, 2013
Mutation linked to pediatric brain cancer

Oren J. Becher, MD (Damon Runyon Clinical Investigator ’12-’15) of Duke University, Durham, Laura A. Banaszynski, PhD (Angelo Family Fellow ‘08-‘11) of The Rockefeller University, New York, and colleagues, reported results that, for the first time, link a mutated histone protein to a rare brain stem cancer in children called diffuse intrinsic pontine gliomas (DIPG). This histone typically silences expression of certain genes; when the histone is mutated in DIPG, cancer-promoting genes are aberrantly turned on. This study was published in the journal Science