New Discoveries and Honors in Cancer Research

Read the latest cancer research and recognition from the members of the Damon Runyon scientific circle.
August 2, 2012
Gene copy number linked to testicular cancer

Zsofia K. Stadler, MD (Damon Runyon Clinical Investigator ‘11-‘14) of Memorial Sloan-Kettering Cancer Center, New York City, led a genomic study of testicular cancer that identified “copy number variations” (CNVs) as a cause of cancer. Rather than being triggered by a single gene mutation, these tumors can be caused by CNVs (too many or too few copies of a gene). CNVs occurred spontaneously in 7% of patients with early-onset testicular germ cell tumors. These findings were published in The American Journal of Human Genetics