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Damon Runyon has announced its 2024 Quantitative Biology Fellows, four exceptional early-career scientists who are bringing cutting-edge computational tools to bear on some of the most important questions in cancer biology. From the packaging of DNA to mechanisms of chemotherapy resistance, their projects aim to shed light on these fundamental questions through large-scale data collection, mathematical modeling, and quantitative analysis.
Just as the study of a growing plant or animal must take into account its environment, cancer researchers must look beyond a tumor to understand how the surrounding tissue impacts its development. In the case of gliomas, the most common and aggressive type of brain tumor, this means looking at neurons—what signals they emit, and how these signals may play a role in brain tumor progression.
A recent study by former Damon Runyon-Sohn Fellow Kathryn R. Taylor, PhD, and her colleagues at Stanford University sheds new light on these questions.
Renal cell carcinoma ranks among the top ten most common cancers globally, with the clear cell subtype (ccRCC) accounting for the majority of metastatic cases. While some ccRCC tumors respond to immunotherapy treatment, it is often difficult to predict which patients will benefit. But those who do likely have something else in common—which is why, as with many problems involving pattern recognition, researchers are turning to artificial intelligence (AI) to help them figure out what this “something” is.
Damon Runyon scientists and industry partners gathered on Thursday, March 7, for the 2024 Accelerating Cancer Cures Symposium, hosted by AbbVie on their campus in South San Francisco.
The Damon Runyon Cancer Research Foundation has named 14 new Damon Runyon Fellows, exceptional postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators. The prestigious, four-year Fellowship encourages the nation's most promising young scientists to pursue careers in cancer research by providing them with independent funding ($300,000 total) to investigate cancer causes, mechanisms, therapies, and prevention.
The Damon Runyon Cancer Research Foundation has announced eight recipients of the 2024 Damon Runyon-Rachleff Innovation Award, established to support “high-risk, high-reward” ideas with the potential to significantly impact the prevention, diagnosis, or treatment of cancer. Five extraordinary early-career researchers will receive initial grants of $400,000 over two years, and each will have the opportunity to receive two additional years of funding (for a potential total of $800,000).
On Saturday, February 10, 2024, an intrepid team of twenty scientific luminaries led by biotech journalist and mountaineer Luke Timmerman embarked upon the trip of a lifetime—a hike to the summit of Mt. Kilimanjaro, the African continent’s highest peak. In advance of the expedition, the team trained for hiking at more than 19,000 feet above sea level, enlisted the support of friends and colleagues, and together raised more than $1 million to support Damon Runyon’s brave and bold cancer researchers.
The Damon Runyon Cancer Research Foundation and St. Jude Children’s Research Hospital today announce the inaugural class of pediatric cancer research fellows. Each of the five fellows will receive funding for four years ($300,000 total) to support an innovative project in basic or translational research with the potential to significantly impact the diagnosis or treatment of one or more pediatric cancers.
Only about one percent of the human genome contains what we recognize as protein-coding genes: DNA sequences that are transcribed into RNA sequences and then translated into proteins. Much of the intervening space between genes consists of mobile DNA sequences, known as transposable elements, which have the ability to “copy and paste” themselves throughout the genome.
Metastatic pancreatic cancer is often resistant to chemotherapy-based treatments, and clinicians do not currently have a good way to predict whether a patient’s cancer will respond or not. At the Abramson Cancer Center of the University of Pennsylvania, former Damon Runyon-Rachleff Innovator Gregory L. Beatty, MD, PhD, and his colleagues are seeking to uncover the factors that determine response so that patients and clinicians can make better informed treatment decisions.
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