Current and Former Awardees
Accelerating Cancer Cures Omar Abdel-Wahab, MD
"Understanding and targeting altered histone modifiers in the myeloid malignancies"
at Memorial Sloan Kettering Cancer Center
Todd A. Aguilera, MD, PhD
"Immunologic responses to short course radiotherapy in rectal adenocarcinoma and the impact of CD40 agonist immunotherapy"
at University of Texas Southwestern Medical Center
Arash Ash Alizadeh, MD, PhD
"Targeting the malignant reprograming of early hematopoietic progenitors to mature aggressive human B-cell lymphomas"
at Stanford University School of Medicine
Vivek K. Arora, MD, PhD
"Defining a targetable oncogenic dyad in bladder cancer"
at Washington University
Sylvan C. Baca, MD, PhD
"Epigenetic drivers of resistance to novel therapies for bladder and kidney cancer"
at Dana-Farber Cancer Institute
Pavan Bachireddy, MD
"Immune evasive circuits that define MRD progression in myelodysplastic syndrome"
at The University of Texas MD Anderson Cancer Center
Vinod P. Balachandran, MD
"Recombinant interleukin-33 immunotherapy for pancreatic cancer"
at Memorial Sloan Kettering Cancer Center
Christopher E. Barbieri, MD, PhD
"Subtype-specific modes of clinical and molecular progression in prostate cancer"
at Weill Cornell Medicine
Oren J. Becher, MD
"Regional differences in central nervous system gliomagenesis"
at Northwestern University
Himisha Beltran, MD
"Utilizing genome sequencing to elucidate mechanisms of resistance in advanced prostate cancer"
at Weill Medical College of Cornell University
Ami S. Bhatt, MD, PhD
"Applying microbiome-based therapeutics in cancer patients"
at Stanford University
Collin M. Blakely, MD, PhD
"Mechanisms of incomplete response and primary resistance to the 3rd generation EGFR inhibitor osimertinib in lung cancer"
at University of California, San Francisco
Marie Bleakley, MD, PhD
"Segregating the GVL effect from GVHD in humans"
at Fred Hutchinson Cancer Research Center
Adrienne A. Boire, MD, PhD
"Molecular determinants of leptomeningeal metastasis: a translational approach"
at Memorial Sloan Kettering Cancer Center
Kelly L. Bolton, MD, PhD
"The use of ivosidenib in IDH1-mutated clonal cytopenia of undetermined significance"
at Washington University School of Medicine
Priscilla K. Brastianos, MD
"Investigation of novel targeted therapeutic approaches for brain metastases"
at Massachusetts General Hospital
Joshua Brody, MD
"Flt3L-primed 'in situ' vaccination for low-grade lymphoma - Phase I/II study of intratumoral injection of rhuFlt3L and poly-ICLC with low-dose radiotherapy [NCT01976585]"
at Icahn School of Medicine at Mount Sinai
L. Elizabeth Budde, MD, PhD
"Targeting CD123 using chimeric antigen receptor T cells for treatment of acute myeloid leukemia"
at City of Hope
Brian C. Capell, MD, PhD
"Defining the role of epigenetic enhancer dysfunction in epithelial carcinogenesis"
at University of Pennsylvania, Philadelphia
Sarat Chandarlapaty, MD, PhD
"Therapeutic approaches to PI3K-AKT-mTOR feedback pathways in breast cancer"
at Memorial Sloan Kettering Cancer Center
Aude G. Chapuis, MD
"Multifaceted transgenic TCR approach to high-risk AML"
at Fred Hutchinson Cancer Research Center
Jaehyuk Choi, MD, PhD
"Development of novel therapeutic strategies for aggressive CTCL subtypes"
at Northwestern University
Ryan B. Corcoran, MD, PhD
"Defining novel targeted therapy combination strategies for BRAF V600 mutant colorectal cancer"
at Massachusetts General Hospital
Marco L. Davila, MD, PhD
"The development and clinical translation of an armored CAR T cell therapy for immune-resistant B cell malignancies"
at H. Lee Moffitt Cancer Center
Daniel J. Delitto, MD, PhD
"Pathogen sensing in fibroblasts restrains antitumor immunity in pancreatic cancer"
at Stanford University
Gavin P. Dunn, MD, PhD
"Characterizing the immunogenic landscapes of malignant brain tumors"
at Washington University
Karuna Ganesh, MD, PhD
"Leveraging patient-derived organoid models to define the molecular determinants of metastatic regeneration"
at Memorial Sloan Kettering Cancer Center
Alejandro Gutierrez, MD
"Mechanisms and therapeutic targeting of EZH2-dependent chemoresistance in T-ALL"
at Boston Children's Hospital
Matthew D. Hellmann, MD
"Refining disease states in response to PD-1 blockade to inform rational immunotherapeutics in NSCLC"
at Memorial Sloan Kettering Cancer Center
Alexander C. Huang, MD
"Shared antigen and neoantigen-specific T cells in checkpoint blockade efficacy and toxicity"
at University of Pennsylvania
Andrew M. Intlekofer, MD, PhD
"Metabolic coupling of the hypoxic niche to stemness"
at Memorial Sloan Kettering Cancer Center
Andrew L. Ji, MD
"Dissecting spatial crosstalk in squamous cell carcinoma arising in organ transplant recipients"
at Icahn School of Medicine at Mount Sinai
Anusha Kalbasi, MD
"IL13Ra2 Chimeric Antigen Receptor (CAR) T cells for metastatic melanoma"
at Stanford University School of Medicine
Jennifer M. Kalish, MD, PhD
"Epigenetic and genetic mechanisms of cancer in Beckwith-Wiedemann Syndrome"
at Children's Hospital of Philadelphia
Alex Kentsis, MD, PhD
"Mechanism and function of regulatory signaling in acute myeloid leukemia"
at Memorial Sloan Kettering Cancer Center
Christopher A. Klebanoff, MD
"Clinical development of next-generation T cell receptor (TCR)-based adoptive immunotherapies for the treatment of patients with common epithelial malignancies"
at Memorial Sloan Kettering Cancer Center
Birgit Knoechel, MD, PhD
"Mechanisms of CD8+ T-cell dysfunction and its therapeutic targeting in T-ALL"
at Dana-Farber Cancer Institute
Xiuning Le, MD, PhD
"Structure- and lineage-based classification and targeting of resistance in EGFR-mutant NSCLC"
at The University of Texas MD Anderson Cancer Center
Piro Lito, MD, PhD
"Modeling responses to targeted ERK signaling inhibition at the single-cell level"
at Memorial Sloan Kettering Cancer Center
Christine M. Lovly, MD, PhD
"Developing novel therapeutic strategies for ALK-fusion positive lung cancer"
at Vanderbilt University
David G. McFadden, MD, PhD
"Identifying metabolic vulnerabilities in Hürthle cell carcinoma"
at University of Texas Southwestern Medical Center
Luc G. Morris, MD
"Functionalizing tumor suppressor gene mutations and deletions in head and neck cancer"
at Memorial Sloan Kettering Cancer Center
Yvonne M. Mowery, MD, PhD
"Evaluating and targeting pathways of treatment resistance in head and neck squamous cell carcinoma"
at University of Pittsburgh
Ann Mullally, MD
"Determining the role of aberrant growth factor signaling in maintaining disease-propagating cells and mediating JAK2 inhibitor resistance in myeloproliferative neoplasms"
at Brigham and Women's Hospital
Benjamin A. Nacev, MD, PhD
"Understanding and targeting chromatin reorganization in ATRX deficient sarcomas"
at University of Pittsburgh
Deepak Nijhawan, MD, PhD
"Using chemistry to identify new targets in lung cancer"
at University of Texas Southwestern Medical Center
Stephen T. Oh, MD, PhD
"Leveraging NFkB pathway dysregulation for therapeutic benefit in myeloproliferative neoplasms"
at Washington University
David Y. Oh, MD, PhD
"Co-receptors modulating anti-tumor activity of human cytotoxic CD4+ effector cells"
at University of California, San Francisco
Matthew G. Oser, MD, PhD
"Dissecting and therapeutically exploiting synthetic lethality between NOTCH and TRIM28 to drive anti-tumor immunity in SCLC"
at Dana-Farber Cancer Institute
Geoffrey R. Oxnard, MD
"Clinical translation of plasma cell-free DNA (cfDNA) genotyping technologies for NSCLC care"
at Dana-Farber Cancer Institute
Phillip L. Palmbos, MD, PhD
"Targeting TRIM29 to reverse immune checkpoint inhibitor resistance in bladder cancer"
at University of Michigan
Sangeetha M. Reddy, MD
"Multi-modality approach to enhancing antigen presentation in breast cancers"
at University of Texas Southwestern Medical Center
Kavita Y. Sarin, MD, PhD
"Genetic contributions and novel therapies for individuals with frequent basal cell cancer"
at Stanford University
Fyza Y. Shaikh, MD, PhD
"Defining microbiome stability and longitudinal shifts as biomarkers of tumor response to immune checkpoint inhibitors across multiple malignancies"
at The Johns Hopkins University School of Medicine
Mark G. Shrime, MD, MPH, PhD
"Cash transfers for cancer surgery in West Africa: their health and economic consequences"
at Massachusetts Eye and Ear Infirmary
Nathan Singh, MD
"Tailored cellular engineering to overcome costimulation-driven CAR T cell dysfunction"
at Washington University
Catherine C. Smith, MD
"RNA Polymerase II as therapeutic target in AML with RAS activation"
at University of California, San Francisco
Melody Smith, MD
"Regulatory mechanisms of the intestinal microbiome on chimeric antigen receptor T cells"
at Stanford University
Zsofia K. Stadler, MD
"Genomic assessment of de novo germline cancer susceptibility in pediatric malignancies"
at Memorial Sloan Kettering Cancer Center
Jean Y. Tang, MD, PhD
"Mechanisms of acquired resistance to Hedgehog pathway inhibitors in basal cell carcinomas"
at Stanford University
Cameron J. Turtle, MD, PhD
"The impact of the colonic microbiota on reconstitution of CD161hi cells and clinical outcomes after allogeneic hematopoietic stem cell transplantation"
at Fred Hutchinson Cancer Research Center
Eliezer M. Van Allen, MD
"Dissecting response to conventional and emerging DNA damage and repair therapies"
at Dana-Farber Cancer Institute
Santosha A. Vardhana, MD, PhD
"Overcoming metabolic suppression of anti-tumor immunity in gastric cancer"
at Memorial Sloan Kettering Cancer Center
Aaron D. Viny, MD
"Epigenetic coupling of DNA methylation and chromatin structure on leukemic transformation and therapeutic response"
at Columbia University
Daniel R. Wahl, MD, PhD
"Targeting metabolic interactions in the glioblastoma microenvironment to overcome therapy resistance"
at University of Michigan
