Clinical Investigator
"Defining and exploiting the cancer surfaceome landscape for novel therapeutics"
University of California, San Francisco
"Targeting intrinsic immune signaling in pancreatic cancer with small molecule therapeutics"
Stanford University School of Medicine
"Pathogen sensing in fibroblasts restrains antitumor immunity in pancreatic cancer"
Stanford University
"Targeting cancer-associated aberrant RNA to treat metastatic melanoma"
Dana-Farber Cancer Institute
"Improving outcomes for patients with hepatocellular carcinoma and liver disease by circumventing myeloid cell-mediated suppression"
University of California, San Francisco
"The role of RecQ helicases in premalignant hematopoiesis and myeloid neoplasia"
Massachusetts General Hospital
"COPS5 as a novel therapeutic target in platinum-resistant ovarian cancer"
Washington University
"Defining follicular lymphoma transformation: molecular basis, detection and therapeutic vulnerabilities"
Dana-Farber Cancer Institute
"Therapeutic opportunities and biological mechanisms for protein-RNA dyssynchrony in medulloblastoma"
University of Michigan, Ann Arbor
Defining and targeting transcriptional drivers of KRAS inhibitor resistance in pancreatic cancer
Dana-Farber Cancer Institute
"Unraveling resistance to bispecific T-cell engagers"
Oregon Health & Science University
"Tailored cellular engineering to overcome costimulation-driven CAR T cell dysfunction"
Washington University
"Predicting leukemia risk from peripheral blood smears"
Dana-Farber Cancer Institute
Dale Frey Scientist
“Dietary nutrients and metabolism shape intestinal regeneration and tumorigenesis”
Massachusetts Institute of Technology
“Imaging and engineering of cellular communication in the brain and tumors”
Stanford University School of Medicine
“The function of interoceptive circuits in reproduction and cancer”
Harvard Medical School
“Catching transcription factors for degradation via the midnolin-proteasome pathway”
Dana-Farber Cancer Institute / Harvard Medical School
"Targeting membrane enzymes for next-generation precision medicine against cancer"
University of Texas Southwestern Medical Center
“Stress granule regulators and their roles in cancer progression”
University of Colorado Boulder
“Epigenetic regulation of neuronal function in response to aging and the environment”
Princeton University
“Rewiring cell-cell communication using engineered scaffold proteins”
University of California, San Francisco
"Mechanisms of retrotransposon spread and regulation and their applications in gene therapy"
Columbia University
“Illuminating error correction strategies in early development”
University of Pennsylvania
Fellow
"Unraveling the cellular and molecular determinants of hematopoietic aging and regeneration in stem cell transplantation"
Boston Children's Hospital
"Mutation-specific TP53 effects on Genome Doubling and cGAS Activation in High Grade Serous Ovarian Cancer"
Memorial Sloan Kettering Cancer Center
"Expansion of the glueable and degradable targets of IMiD-CRBN"
Dana-Farber Cancer Institute
"Integrin a6ß4 in hemidesmosome dynamics: structural and functional insights for tissue homeostasis, organoid growth, and cancer"
Boston Children's Hospital
"Identifying the design principles of immunological synapse to engineer the antigen sensitivity and effector functions of CAR T cells"
Whitehead Institute for Biomedical Research
"Investigating molecular and cellular mechanisms of intra-tumoral heterogeneity in small-cell lung cancer"
Stanford University
"De novo design of protease-activated anticancer proteins"
University of California, San Francisco
"Changes in translation start site selection as feature and driver of lymphoma"
Whitehead Institute for Biomedical Research
"Defining how early-life microbial encounters sculpt the B cell repertoire and shape vaccine responses"
University of California, Berkeley
"Mechanisms and consequences of microbiota-directed immune responses"
University of California, Berkeley
"In situ organization of sensory receptors that mediate acute and chronic pain"
University of California, San Francisco
"Using hyperactive dendritic cells to generate improved cancer vaccines"
Boston Children's Hospital
"Leveraging polyploid Xenopus to probe spindle adaptation to increases in genome size"
University of California, Berkeley
"Control of gamma delta T cell anticancer activity by bacterial infection"
University of California, Berkeley
"Uncovering signaling mechanisms in somitogenesis through high-throughput genetic screens in robust human organoids"
Harvard University
"Decoding the transcription code: de novo protein design for precise gene regulation"
University of Washington
"Genetic engineering of oncolytic viruses for pyroptosis-accelerated cancer virotherapy"
Massachusetts Institute of Technology
"Integration on oncogenic signaling and nutrient sensing by mTOR in tumors"
Harvard T.H. Chan School of Public Health
"Identifying fibroblast stem cells in organ maintenance, repair, and cancer"
Stanford University
"Elucidating mechanisms that reverse the detrimental effect of RAS mutations in cancer"
Memorial Sloan Kettering Cancer Center
"From tools to tumors: building genetic systems to determine Prevotella's role in cancer"
Geisel School of Medicine at Dartmouth
"Deciphering the impact of tumor-colonizing microbiota"
Dana-Farber Cancer Institute
"Examining bacteria as a source of tumor antigens"
Massachusetts Institute of Technology
"Examining bacteria as a source of tumor antigens"
Massachusetts Institute of Technology
"Investigating therapeutic vulnerabilities of lung cancer by tracking cellular identity"
Massachusetts Institute of Technology
"Targeted chemical aggregation as a general strategy to overcome cancer drug resistance"
University of California, San Francisco
"Defining mechanisms by which quorum sensing and 3D morphogenesis interact in space and time to drive Vibrio cholerae pellicle maturation"
Princeton University
"Immunologic targeting of 'undruggable' TP53 hotspot mutations through T cell receptor gene therapy"
Memorial Sloan Kettering Cancer Center
"Understanding and engineering combinatorial gene regulation in mammalian cells"
California Institute of Technology
"Host–microbe bidirectional metabolism of dietary xenobiotics and its role in cancer risk"
Yale University
"Reverse transcriptase and DNA polymerase coordination during antiviral immunity"
Columbia University
"Elucidating the lineage relationships of thymic mimetic cells"
Harvard Medical School
"The collective cellular mechanics of tissue homeostasis"
The Scripps Research Institute
"Synthetic intercellular signaling circuits for threat sensing and response"
California Institute of Technology
"Spatial mechanical regulation of oncogenic signaling in tumor progression and metastasis"
University of California, San Francisco
"A Systematic Approach for Targeting Protein Complexes in Lung Cancer"
Massachusetts General Hospital
"Developing Tools to Mechanistically Investigate the mtDNA 'Common Deletion'"
Memorial Sloan Kettering Cancer Center
"ATM kinase orchestrates transcription silencing and anti-tumor immune responses"
University of Pennsylvania, Perelman School of Medicine
"Mechanisms of chromosome fragmentation generating chromothripsis"
Dana-Farber Cancer Institute / Harvard Medical School
"A general platform for preparation and study of 3O-sulfated sugars"
Harvard University
"Development of haptenizing chimeras for neoantigen generation"
The Broad Institute of MIT and Harvard
"Hepatic urea cycle function in NASH-induced HCC progression"
University of Pennsylvania
"Revealing structure and function of an anomalous bacterial secretion system throughout the host cell"
Massachusetts Institute of Technology
"Selfish persistence within a (super)organismal host"
California Institute of Technology
"Formation, excision and cytoplasmic export mechanisms for pathological R-loops"
Stanford University
"Investigating the neural mechanisms that drive skeletal pain"
University of California, San Francisco
"Determining the Germline Genetic Impact on Somatic Evolution of ERBB2 in Human Cancer"
The Broad Institute of MIT and Harvard
"Enter and persist: enhancing anti-tumor T-cell infiltration and metabolism in the brain"
The Salk Institute for Biological Studies
"Deciphering the molecular and structural mechanism of dynein +TIP tracking"
University of Michigan
"Targeting age-driven myeloid dysfunction in cancer: unraveling the immunomodulatory and metabolic contributions of GLP-1R agonists"
Icahn School of Medicine at Mount Sinai
"Elucidating PABPC1 sequence preferences and determining how these preferences shape gene regulation"
Whitehead Institute for Biomedical Research
"Elucidating the mechanism of inosine-dependent inhibition of RIG-I-like receptor filamentation and interferon signaling"
University of Utah
"How do eukaryotic cells count cell cycles? Intrinsic regulation of quantized asexual replication cycles and commitment to sexual differentiation in the protozoan parasite Cryptosporidium parvum"
University of Pennsylvania
"Elucidating what determines the strength of bacterial transcription terminators"
Massachusetts Institute of Technology
"Structurally resolving the metabolism of cancer treatments by P450 enzymes”
University of California, San Francisco
"Dissecting cancer and immune cell metabolic activity within tumors"
Princeton University
"Humanize CXCL13 expression in mouse to understand lymphoid neogenesis in cancer"
University of California, San Francisco
"Targeting Clostridioides difficile biofilm dynamics to combat recurrent infections"
Vanderbilt University Medical Center
"Dissecting heterogeneous cellular responses to oncogenic KRAS inhibition in pancreatic adenocarcinoma"
Memorial Sloan Kettering Cancer Center
"Elucidating the contributions of diet and exercise on the redox environment of the gut"
Stanford University School of Medicine
"Endogenous retroviruses modulation of intestinal immune homeostasis and tumor development"
National Institutes of Health
"Defining the molecular landscape and native interactome of the Siglec-sialoglycan axis in disease"
Stanford University
"Discovery and characterization of bacteriophage effectors of bacterial immune systems"
Massachusetts Institute of Technology
"Regulatory T cells in health and disease: from Foxp3 dependence to resilience and back again"
Memorial Sloan Kettering Cancer Center
"Decoding cell-cell interactions aiding angiogenesis and immune evasion in early-stage lung cancer"
Boston Children's Hospital
"Mitochondrial ubiquitylation mechanisms to exploit metabolic vulnerabilities in cancer"
University of California, Berkeley
"Cellular structural biology of an evolutionarily-ancient organizer of cell shape and movement"
University of California, San Francisco
"Investigating neutrophil functional heterogeneity in wound healing and cancer"
University of Calgary
"Neuroimmune: cancer stem cell interactions in the tumor microenvironment"
The Rockefeller University
"Spatiotemporal regulation of eDNA release in Pseudomonas aeruginosa biofilms"
California Institute of Technology
"High-throughput precision genome editing for dissecting complex traits in yeast and human cell lines"
Stanford University School of Medicine
"Mechanistic interrogation of robustness and vulnerability in a bacterial essential gene network"
Harvard Medical School
"From form to function: Cell shape, cell ordering, and gene regulation in bacterial biofilm"
Yale University / Michigan State University
"Dissecting dynamic cellular responses to genetic perturbations using time-resolved single-cell CRISPR screens"
Memorial Sloan Kettering Cancer Center
"Investigating innate immune activation in the autoimmune pancreas"
University of Washington
"IL25 induced tissue resilience in the prevention of colorectal cancer and therapy-induced adverse events"
University of California, San Francisco
"Identifying the selective mechanism behind U2AF1 mutations in lung adenocarcinoma"
Dana-Farber Cancer Institute
"Dissecting the molecular identity and contents of neuronal synapses using spatially resolved RNA sequencing"
The Broad Institute of MIT and Harvard
"Understanding CD8 T cell epigenetic changes fueled by S-adenosylmethionine metabolism for improved adoptive cell therapy"
Van Andel Institute
"Identifying cytoplasmic nucleases that shatter micronucleated chromosomes"
University of California, San Diego
"Filming mechanochemical cycles of ring ATPase: Phi 29 DNA packaging motor as an example"
University of California, Berkeley
"Spatial organization and inheritance regulation of oncogenic extrachromosomal DNA (ecDNA)"
Stanford University School of Medicine
"Developing an activity-based sensing probe for selective monitoring ammonia in cancer"
Princeton University
"Mechanism of asymmetric chromosome segregation in germline stem cells"
Whitehead Institute for Biomedical Research
"Microbiome-Cancer Connection: From Understanding to Rational Design with Defined Communities"
Stanford University
"Preventing tumor evasion of CAR T killing: engineering adhesion molecules to enhance cell immunotherapy"
University of California, San Francisco
"Understanding the role of R-loops in cancer at the single cell level"
Memorial Sloan Kettering Cancer Center
"Illuminate and Inhibit Cancer Progression at Single-Molecule Precision"
The Broad Institute of MIT and Harvard
"An integrated imaging- and sequencing-based spatial-omic method to study tumor evolution"
Whitehead Institute for Biomedical Research
"Mapping and modeling the human CD4+ T cell differentiation gene regulatory network"
Gladstone Institutes
"Charting the tumor antigen landscape of breast cancer"
Brigham and Women's Hospital
Innovator
"Developing targeted therapeutics in cancer copy number space: reduce gene dosage vulnerabilities"
University of Pennsylvania
"Decoding and reprogramming dendritic cell function for solid tumor immunity"
University of California, San Francisco
"Skin commensal bacteria as a novel source of systemic antitumor immunity"
The Broad Institute of MIT and Harvard
"Defining the interactions between NKT cells, tumors, and lipid antigens"
Saint Louis University
"Tools to target novel cell surface ligands in cancer"
Boston Children's Hospital
"Nibbled to death: improving macrophage's ability to kill solid tumors by trogocytosis"
University of California, Santa Barbara
"Leveraging zebrafish models to overcome blood-brain barrier in glioblastoma treatment"
Rutgers University
"Tumor-macrophage metabolic symbiosis as a driver of disease progression and therapeutic resistance"
Memorial Sloan Kettering Cancer Center
"Ex situ maintenance of intact human organs to study tumor biology"
Icahn School of Medicine at Mount Sinai
“Identifying and disrupting the bioelectric circuits driving brain cancer”
Brigham and Women's Hospital
"X marks the spot: exploring how X-chromosome alterations drive sex differences in cancer"
Dana-Farber Cancer Institute
"A discovery platform for engineering T cells that serially kill"
Children's Hospital of Philadelphia
"Unveiling the tumor antigenome through immune intelligence"
New York University School of Medicine
“Chemical stimulation of GTP hydrolysis for oncogenic Ras mutants and beyond”
University of California, Berkeley
Physician-Scientist
"The role of inflammatory signaling in the pathogenesis and therapeutic targeting of RAS-mutated AML"
Cincinnati Children's Hospital Medical Center
"Investigating chromatin architectural dynamics mediated by LDB1 in T-cell acute lymphoblastic leukemia"
University of Pennsylvania
"Understanding the role of KMT2D in MLL-AF9 acute myeloid leukemia"
The Rockefeller University
"Epigenetically targeting MYC through paradoxical nuclear receptor activation in hormone-dependent malignancies"
Massachusetts General Hospital
Reprogramming ovarian TIL with gene fusions to overcome immune resistance
University of California, San Francisco
Modulating metabolic and microbial pathways to mitigate immune-related colitis
The Johns Hopkins University School of Medicine
Understanding mechanisms of transcriptional regulation and uncovering novel dependencies in NPM1-mutant AML
Fred Hutchinson Cancer Research Center
"Origin and evolution of long-lived CAR T cells in patients with hematologic malignancies"
Memorial Sloan Kettering Cancer Center
"Leveraging memory-like T-cell phenotypes to improve cellular therapies"
The University of Chicago
"Uncovering microenvironmental dependencies in follicular lymphoma"
Brigham and Women's Hospital
"Defining the mechanistic implications of SF3B1 mutations in MDS"
Dana-Farber Cancer Institute
"Elucidating the role of KAT6A and KAT6B in the epigenetic reprogramming of neuroblastoma to enforce neuronal differentiation"
Dana-Farber Cancer Institute
"Defining the mechanism of thrombosis in patients with multiple myeloma"
Dana-Farber Cancer Institute
Quantitative Biology Fellow
"Optimal epigenetic therapies in triple-negative breast cancer"
Dana-Farber Cancer Institute
"A probabilistic framework for deconvolving causal mechanisms of cancer therapeutics with genetic perturbation screens"
New York Genome Center
A graph neural network predicting breast cancer risk using aneuploid cells in normal breast tissues
The University of Texas MD Anderson Cancer Center
"Generative artificial intelligence enabling next-generation radiopharmaceuticals"
Memorial Sloan Kettering Cancer Center
Interrogating microbial metabolism under hyperoxic stress during pneumonia in immunocompromised patients
Fred Hutchinson Cancer Research Center
Genomic and functional interrogation of recurrent X chromosome copy number gains in cancer
Dana-Farber Cancer Institute
"The biophysics of substrate recognition in chromatin remodeling"
Princeton University
"Chromosome structure remodeling in innate immune training and gene regulation"
University of California, Los Angeles
"Signal bottleneck theory for dissecting gene interactions in pancreatic cancer"
Dana-Farber Cancer Institute
"Single-molecule sequence models to decode regulatory genome in cancers"
The University of Chicago
"Geometric modeling of perturbed gene regulation dynamics across time and space"
New York Genome Center
St. Jude
"Investigation of DNA ligase I as a therapeutic vulnerability in Ewing sarcoma"
Dana-Farber Cancer Institute
"Investigation of receptor tyrosine kinase-independent mechanisms of FGFR1-mediated oncogenesis in pediatric gliomas"
Dana-Farber Cancer Institute
"Addressing antigen heterogeneity in pediatric gliomas with tumor-assimilating multispecific immune cell engagers"
"Single-cell profiling of cytoskeletal properties to enhance Ewing sarcoma immunotherapy"
William Marsh Rice University
"The N-Ras palmitoylation cycle as a therapeutic target in pediatric acute myeloid leukemia"
University of California, San Francisco
"Improving regulatory T cell activity in chronic GVHD using thalidomide analogs"
Dana-Farber Cancer Institute
"Investigating the neuronal regulation of radioresistance in diffuse midline gliomas"
Dana-Farber Cancer Institute
"Investigating the role and therapeutic potential of microbiome and bile acids in immune recovery and graft-versus-host disease in pediatric allogeneic transplantation"
Memorial Sloan Kettering Cancer Center
"Application of single-cell approaches to investigate the developmental origin and early transformation steps of osteosarcoma"
Dana-Farber Cancer Institute
"Enhancing immune synapse formation with synthetic adhesion to overcome chimeric antigen receptor-T cell resistance in pediatric B cell malignancies"
University of California, San Francisco
"Enhancing specificity and function of memory-like NK cell therapy in acute myeloid leukemia"
Washington University
"Identifying mechanisms of immune evasion in a murine model of osteosarcoma"
Dana-Farber Cancer Institute
"Decoding mechanisms of B-acute lymphoblastic leukemia pathogenesis through the lens of genomics"
Dana-Farber Cancer Institute
"Targeting TFE3-fusion oncoproteins in pediatric kidney cancer: mechanisms, modulators, and therapeutic vulnerabilities"
Dana-Farber Cancer Institute
"Functional characterization of tumor neuronal networks that drive ependymoma"
St. Jude Children's Research Hospital
SPARK Scholar
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